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Comparability of treatment groups at baseline were compared using a multi-way ANOVA for continuous variables and logistic regression for categorical variables.
A comprehensive discussion is given of the elements in the comparative clinical trial (phase III), including objectives, consierations in planning (comparability of treatment groups stratification of patients, feasibility and size of study, and prospective versus retrospective studies).
Six studies reported the comparability of treatment (except the introduction of CHWs).
Most comparisons between ketoconazole and other antifungals were based on single studies that showed comparability of treatment effects.
They can also be used to define strata in clinical trials to ensure comparability of treatment groups.
Finally, completion rates and item missing rates at different time points were not different between study arms, providing further support for the comparability of treatment groups.
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Moreover, head-to-head comparisons of treatments were infrequent, making it difficult to evaluate the comparability of treatments.
To ensure the comparability of treatments, treatment dose, application and assessment occasions for SEPT and ACG will be identical.
Other observational studies on the comparability of homeopathic treatment and conventional treatment of upper respiratory tract infections (URTI) have shown positive outcomes for homeopathy [ 15, 16].
Baseline characteristics were compared, to assess comparability of the treatment groups at trial entry.
Making cost-effectiveness comparisons across available first-line chemotherapy treatments is limited by the comparability of the treatment populations and the short time frames.
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