No significant differences in comparability of the two methods were noted between high- and low-resistance areas.
Yet, it should be noted that the comparability of the two studies is limited since they differ in the virus strains used for vaccine production and the method by which vaccine stability was assessed (in vivo immunogenicity versus SRID (31)).
Finally, from a methodological perspective, the review noted that the comparability of the findings across countries and over time was hampered in many cases by the use of different indicators of the burden of OOP spending both within and across countries and different studies.
While the use of standardized questionnaires offered the advantage of enhancing cross-national comparability of the results, some limitations were noted, especially in relation to the categories used for occupations and qualifications that did not necessarily conform to the country situation.
We take in the above theorem and note that the weak comparability of and reduces to (2.36).
Although use of a standard tool greatly enhanced the comparability of results across studies, a common methodological limitation noted in the review was the failure to evaluate the effect of mental health comorbidity.
While the use of standardized questionnaires offered the advantage of enhancing cross-national comparability of the eventual survey responses, some limitations were noted, especially in relation to the predefined occupational categories that did not necessarily conform to the country situations.
It has to be noted that in these interventional studies differences in methodology also limit comparability of the results.
Overall, no significant differences were noted between PN and non-PN recipients at baseline, supporting the general comparability of patients prior to PN initiation.
Second, as noted above, the review included a wide range of community support initiatives reducing the comparability of the outcomes.
The Korean FDA guidelines note that receptor-binding studies or cell-based assays should normally be undertaken to establish the comparability of the biological/PD activity of the biosimilar and the reference product.
