Sentence examples for compaction of chromatin from inspiring English sources
HP1β, but not nucleosome spacing or phasing, regulates chromatin rearrangements because it governs both the compaction of chromatin and its interactions with the nuclear envelope.
Such modifications modulate the compaction of chromatin and its general accessibility to transcriptional machinery.
Controlling the level of compaction of chromatin is essential for the regulation of all cellular processes.
It is known that SAP30 also interacts with N-Cor [43] promoting the compaction of chromatin.
The higher compaction of chromatin in the lineage-committed cells is reflected in the differences in DAPI density in the epiblast vs. trophoblast cells (Figure 4D).
The genome of the latter stages is therefore susceptible to at least some types of genotoxic insult, despite protective factors such as the blood-testis barrier and compaction of chromatin.
Cells overexpressing ΔR3, R11A, or ΔR3R11A H2A mutants had increased interprobe distances, indicating de-compaction of chromatin.
Second, our in vivo data with human cell lines shows de-compaction of chromatin in the absence of R11.
It has been speculated that the possibility of a rapid expansion and re-compaction of chromatin domains plays a major role in gene regulation [ 49].
This results in de-compaction of chromatin and greater access to DNA for transcription factors, leading to a transcriptionally active genomic locus.
DOI: http://dx.doi.org/10.7554/eLife.02792.011 Since the H2A NTD in large genomes contains both R3 and R11, we expected that their removal would cause de-compaction of chromatin.
