Communicating cells can coordinate their gene expressions to form spatial patterns, generating order from disorder.
This rudimentary analysis highlights the emergent physiology of a tissue, in this case, peripheral blood, comprising a mixture of communicating cells.
Blood is a containment of communicating cells, tissues and organs in human body.
Therefore they concluded that the distance between communicating cells maximize cellular response fidelity.
In addition, it has become a model system for studying the emergence of coordinated behaviour in communicating cells.
This mechanism could lead to limited and specific activation of communicating cells compared to the activation obtained through the paracrine effects of released cytokines and chemokines.
Above all, one mechanism of cell-cell interaction is direct cell-cell communication via gap junctions, which are transmembrane channels that allow for the continuity of cytoplasm between communicating cells [ 13– 15].
In the context of QS modelling, most research has focused on the understanding of the intracellular circuit [ 7- 11, 21- 24], i.e. single cell studies, while few of them have considered an ensemble of communicating cells [ 25- 28].
The polarity in plants is very important in order to allow our cells to organize themselves into communicating cell files.
These cells communicate through cell contacts, growth factors, cytokines, and extracellular matrix proteins, creating microdomains or niches and regulating their self-renewal, differentiation, and quiescence [ 6].
