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In evaluating the results below, mutator pathways are expected to predominate when α50% is at or below commonly observed values of α (ca. 10 500).
In contrast, when six oncogenic mutations are required for cancer (C = 6), α50% ranges from 11 30 (Supplementary Table S1), in the lower range of commonly observed values of mutation rate increase due to mutator mutations, suggesting a predominance of mutator pathways.
Interestingly, the mycobacterial stasis observed in adipocytes correlated with cell differentiation and accumulation of lipid droplets, as fibroblast-like pre-adipocytes allowed mycobacterial replication with a doubling time of about 40 h (Fig. 1C), which is less than the commonly observed values in macrophages.
In contrast, when six oncogenic mutations are required for cancer (C = 6), α50% ranges from 11 30 (Supplementary Table S1), in the lower range of commonly observed values of mutation rate increase due to mutator mutations, suggesting a predominance of mutator pathways, in that most mutator mutations would then correspond to α>α50%.
The most commonly observed values for VM in protein crystals cluster around 2.15 Å/Da, which corresponds to 43% solvent content.
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The most commonly observed PIC values were between 0.4 and 0.5 (Table 4).
However, considering commonly observed MIC values for community-acquired pathogens, both modes of administration clearly yielded therapeutic drug concentrations.
We found that while the ansamycin compounds have the commonly observed negative value, the nucleotides show a negligible or even a positive ΔCp of binding.
Similar conclusions were drawn by Gorroochurn et al. (2007), who showed that for commonly observed P-value thresholds (P = 0.02 0.01, when α = 0.05), replication probabilities are surprisingly low (around 60 70% chance of replication).
As is commonly observed, the Laplacian values, especially for the polar covalent bonds, show slightly greater discrepancies between theory and experiment.
The PDC had a concentration of inhalable ash particles (<100 microns) in the order of 0.1÷0.7 kg/m3, the lower values commonly observed at the head of dilute PDCs, and temperature range between 250 and 600°C.
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