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While unsupervised methods may show favorable operating characteristics in specialized settings—such as when biological variables contribute relatively negligible signal to the data it has been shown they make assumptions about data that are commonly invalidated in practice (Dabney and Storey, 2007; Irizarry et al., 2006).
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In addition to large LD blocks, fine-mapping studies in model organisms are complicated by population structure (i.e. the complex genetic relationship between different individuals in the study; Flint and Eskin, 2012; Kang et al., 2008; Price et al., 2006) that invalidate commonly used association statistics that assume the individuals in the study are independent.
Unfortunately, such an assumption no longer holds in anisotropic networks which can be commonly found, and this assumption can be invalidated by a variety of factors: obstacles, resource limitation, sparse and non-uniform node distribution, irregular radio propagation pattern, and irregular regions [14].
The absence of a commonly agreed jurisdiction could invalidate the whole enterprise and confirm the fact already evident that political power, not justice, will determine the future.
Epstein (2007) invalidates the commonly cited dichotomy between computational agent-based models and equation-based models by proving, albeit informally, that all computational agent-based models can be expressed using partial recursive functions.
The BP data of 42/185 (22.7%) participants was invalidated due to failure to obtain a good quality trace or due to artefact; most commonly due to external pressure on the finger cuff at the time of the stand.
The district invalidated students' scores.
Should these SAT scores be invalidated?
Some even said it invalidated the project.
His removal could be invalidated.
"The High Court invalidated this criterion".
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CEO of Professional Science Editing for Scientists @ prosciediting.com