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Proteolytic autodigestion: Common tissue pathology in Shwachman-Diamond syndrome?
"Proteolytic autodigestion: Common tissue pathology in Shwachman-Diamond syndrome?" Cell Cycle 12 (22): 3457-3458.
At the fusion of leaf basis and shoot results this enigmatic common tissue.
EBCs are observed in ∼50% of halophytic plants; so they are a common tissue utilized by salinity-tolerant plants to cope with salt.
The lower operation limit of common tissue equivalent proportional counters (TEPCs) is about 0.3 μm in simulated site.
While a significant proportion (54%) of miRNA found to be associated with the gene signatures are the same as for the tumour tissues, which can be expected due to the common tissue origin, the analysis of the targets of these miRNA reveals that they do not show enrichment for TSG in the normal tissue, again highlighting the context dependency in miRNA-mediated gene regulation.
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The KEGG enrichment analysis depicted common, tissue-specific, and time-point-specific patterns of overrepresentation.
As such platform-dependent bias can compromise the data quality; we reasoned that a consolidated list of common tissue-specific genes might yield more reliable results.
Unlike the tissue TF pairs, we did not find any common tissue-type TF-TF interaction networks between different tissue types.
Nell-1 promoter hypermethylation is a common, tissue-specific event in human esophageal adenocarcinoma (EAC), and it is a potential biomarker of a poor prognosis in early-stage EAC [ 23].
As shown in Table 5, depending on the tissue type considered, the percentage of common nodes (number of common nodes/total number of nodes × 100) in a HuGE-derived PPI network varied from 32.8% to 93.5%, while the percentage of common house-keeping nodes and common tissue-specific nodes varied from 8.75% to 31.3% and from 0%too 4.48%, respectively.
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