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Assembled contigs that shared common reads were placed into isogroups.
At a given iteration, since no stars share common reads, the time complexity to generate merged contigs for all stars is O(n).
Thus, allele-specific expression of the B73 and Mo17 alleles can be inferred from the ratio of the amount of unique reads and common reads.
Therefore, we performed a Poisson regression to estimate read coverage for the B73 and Mo17 alleles based on generalized Poisson distribution by considering the amount of B73- and Mo17-unique reads as well as common reads within an allele.
Unspliced aligner can handle common reads which come from major part of genome, certainly allow reads have errors or indels, the highest-profile software are BWA [ 11], Bowtie [ 12], SOAP2[ 13], and so on.
Reads were classified into three groups: (1) reads that were only or preferentially mapped to the B73 genome (B73-unique reads); (2) reads that were only or preferentially mapped to Mo17 (Mo17-unique reads); and (3) reads mapped to both genomes with equal bowtie mapping score (common reads).
Similar(53)
The design solution involves a ROIC matrix formed by 2 × 2-element fragments (cells) in which all the four cell elements, connected to one common read line, share a common integrating capacity.
"What Does (sic) Lance Tyson & Mitt Romney Have in Common?" read one flyer distributed to voters.
Because of common (read: inevitable) instances like this, most people have negative, guilt-inducing associations around the concept of procrastination.
The common read among liberals is that they know their bill is terrible and want to spring it on the public just to pass something and be done with it.
Our findings demonstrate the widely varying abilities of common read alignment tools and their impact on downstream variant calling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com