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The oropharynx (OP) and nasopharynx (NP) are 2 of the most common portals for the introduction of microorganisms into the respiratory tract.
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This extensive exposure to the environment means that the lungs are a common portal for infection by viruses, bacteria, fungi, protozoa and other infectious agents.
This Table lists key protein targets and ligands in this document, which are hyperlinked to corresponding entries in http://www.guidetopharmacology.org, the common portal for data from the IUPHAR/BPS Guide to PHARMACOLOGY (Pawson et al., 2014) and are permanently archived in the Concise Guide to PHARMACOLOGY 2013/14 (Alexander et al, 2013a,b).
In patients with granulocytopenia, the ulcerations that accompany mucositis are common portals of entry for indigenous oral bacteria, often leading to sepsis or bacteremia [ 3].
The most common portals of entry of the diphtheria bacillus are the tonsils, nose, and throat.
Since the umbilical stump blood vessels are exposed for the first few days after birth, they are a common portal of entry for invasive bacteria that cause systemic infections (sepsis) in newborn babies [ 3], which may lead to death.
Of the 4 million annual neonatal deaths, approximately 36% are attributable to infections [ 267] with the cord as a common portal of entry for organisms.
This harmonization should probably be done through common portals and interfaces allowing for future common annotations-types and formats.
The most common portal anatomy was type 1, present in 67.4% of cases (n = 31).
The TBI proteomics core technologies will provide an integrative approach to genomic and proteomics information by developing a common portal architecture; the TBI proteomics portal.
Using this method, we have thoroughly examined the dissociation pathways of different ligands from LFABP and revealed alternative portals, in addition to the common "portal region".
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