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Though he declined to discuss it because his article is due to be published, in the Proceedings of the National Academy of Sciences, colleagues said the theory envisages all three kingdoms emerging independently from a common pool of genes.
Changes in gene expression of a common pool of genes (∼7800) were determined for tetracycline-treated (tet) and untreated (MYC over-expression) human P493-6 B cells for NRO and total RNA using both microarray platforms.
Let us denote by G the common pool of genes that ChIP-chip and knock-out experiments used.
Taken together, our data indicate that a highly common pool of genes is modulated by the two modulators while massive rewiring among these genes exists across different conditions (i.e., ESR1 or ERBB2 alone, and co-modulation).
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Restricting analysis to the common pool of progenitor genes synchronized "Cardiovascular Development" within a streamlined ontological infrastructure, and revealed identities of prioritized network hubs that promoted pluripotent stem cell-derived cardiogenesis.
These data allow rapidly observing a common pool of target genes, possibly regulated by the same HSA21 miRNA.
At the same time, the easily spreading metabolic genes could form a common pool of transferable operational genes [ 200], such that the organisms, depending on their metabolic requirements, could acquire the necessary tools from a common gene pool.
We find that EV of genes is highly similar between different tissues (ExpO dataset) and different conditions (CK dataset), suggesting that a common pool of condition-specific genes may exist, selective modulation of which may drive cell adaptation.
The presence of a common pool of dental plaque genes is not unlikely in light of the results described here.
Although bacteria of the M. tuberculosis group were believed to be resistant to horizontal gene transfer and comprised only ancient genomic islands [ 9, 22], it was still possible to root them to the common pool of mycobacterial horizontally transferred genes.
The functions could be encoded by ancient genes, sharing a common pool of exons, which keep the relationships to each other undetectable by other methods of analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com