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We now know that many quite different diseases share common pathways and processes in the cell.
MapMan (v3.1.1) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway tools were used to visually map cluster of pineapple genes involved in common pathways and processes for both pathway-specific and molecular overview purposes.
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The analysis revealed that miRNAs with highly correlated expression profiles may contribute, via their targets, to common pathways and cellular processes that are characteristic of the tissue in which these miRNAs are predominantly expressed.
Analysis of global gene expression in several environmental conditions revealed an interesting feature of genome regulation: genes involved in common pathways or metabolic processes tend to be coordinately expressed/repressed.
Numerous diseases share common pathways with aging processes.
The use of DAVID enabled the integration of the miRNA target genes into common pathways or GO processes.
We identified pathways and processes that were common to all cancers as well as traits that are unique to a cancer type or closely related cancers.
Combined analysis of the mutated genes revealed set of genes that are mutated in many tumour types (201 genes are mutated in four or more different tumour types), and contribute to core cellular pathways and processes that are common to many tumour types.
Next, we examine common genes, pathways, and physiological processes that when manipulated extend lifespan, and the relationship of these manipulations to stress responses.
Screening for suppressor mutations is a powerful method to isolate genes that function in a common pathway or process.
Screening for genetic suppressors is a powerful method to identify genes that function in a common pathway or process (Hodgkin 2005).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com