The most common investigator-assessed reasons for itraconazole discontinuation were adverse events (23·2%) and study drug intolerance (21·6%).
The most common investigator-assessed drug-related adverse events (AEs) in the THALASSA trial were nausea, skin rash, diarrhea, headache, upper abdominal pain, and abdominal pain (for full details see Ref. 17).
The most common investigator-assessed drug-related AEs observed in each LIC cohort are shown in Table 4.> -wrap-foot> liverver function, mod moderate In the <7 mg Fe/g dw cohort, there was one case of investigator-assessed drug-related severe diarrhea in a patient with MDS.
But Mr. Borrelli does not believe the gadgetry and surveillance tools common to investigators today would have solved the murders.
In fact, Mr. Raissi said it was common for investigators to "look at other traders in the same ZIP codes, area code and establish connections between traders".
While it's common for investigators to turn suspects facing charges into informants in exchange for leniency, they typically work their up to the top of a criminal organization — it's rare to use the boss to set up underlings.
It is increasingly common for investigators to use gene expression signatures directly as phenotypes to link various biological processes and perturbations to disease phenotypes and chemical agents.
Using subcutaneous tumours in laboratory mice is very common among investigators aiming to test various PDT regimens (Table 1).
In light of the evidence supporting a genetic contribution to common OA, investigators have sought to identify genetic variants, or chromosomal regions predicted to contain variants, that contribute to common forms of OA.
It is also becoming increasingly common for investigators to produce specific anti-phosphopeptide antibodies against the phosphorylated residue(s), which provides additional confirmation of the phoshosphorylation, and also allows for simplified detection of the phosphorylation site under various experimental conditions (Tables 2 and 3).
