Furthermore, it can be applied to other cancer types in order to identify the cancer-specific or common interactions among cancer types.
This methodology can be applied to other cancer types in order to identify the cancer-specific or common interactions among cancer types as well as other common, complex diseases.
SlTCP12 and SlTCP18 have 32 common interactions, among which one encodes a member of the DREB subfamily A-2 of ERF/AP2 transcription factor family, another ethylene responsive gene.
For the cell wall, 84 common interactions were identified among the 3 growth conditions, including proteins involved in heat-shock response, sugar and amino acid/protein metabolism and cell signaling.
Next, we looked at protein-protein interaction (PPI) networks, KEGG, and the literature to find common interaction partners among differentially expressed surfaceome genes, as we did in [ 5].
The most common interaction type among curated interactions is "physical association", however, there are also many more specific interaction types including over 700 phosphorylation interactions, more than 300 cleavage interactions, 85 ubiquitination interactions, and smaller numbers of other biochemical interactions including sumoylation, methylation, and acetylation interactions.
We can see that regulatory (up-regulates, down-regulates, regulated by) and activation/inhibition (activates, inhibits, inhibited by) are among the most common interactions.
Lipoprotein FTT0482c interacted with WDR48, which thus was a common host interaction among all the identified virulence factors.
In addition, there also tend to be correlations in common environmental and gene environment interactions among close relatives compared with random, unrelated individuals.
Cooperation and division of labor is a common theme in biology, where interactions among independent agents can give rise to emergent properties21.
The report suggested improving advising and dining options for juniors and seniors who choose to remain in their residential colleges, and creating more common spaces to encourage informal interactions among students.
