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Sex specific effects are quite common in mouse studies, for example PPARγ agonist treatment reduces atherosclerosis lesion areas in male, but not female, LDL receptor-deficient mice [11].
In mouse liver, we found HNF4A1 transcripts to be more common in mouse than in humans or rats (present at 63% in mice v/s 37% in human and 42% in rat; p = 0.05) (figure 4c).
From this it is apparent that new TE insertions are quite common in mouse and rat; the majority of genes have a new LTR, SINE and LINE insertion within 20 kb of the coding region.
Genes highly expressed in both tissues are, therefore, not very common in mouse.
As discussed above, it is not clear yet whether the role of Wnt/β-catenin signaling in liver specification is unique to zebrafish or common in mouse.
Although several genes on the human X chromosome escape inactivation (Carrel & Willard, 2005), this is not common in mouse (Disteche, 1999).
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The researchers also found that certain types of gut microbes were more common in mice fed saccharin.
In a study in which mice were fed on either an iron deficient or iron sufficient diet, with or without added lead, spontaneous seizures were more common in mice on the iron deficient diet with added lead.
Thus, contrary to the prevailing assumption that the transgenes are integrated into the genome in a head-to-tail tandem array with rare exceptions [28], [29], [30], the inverted transgene integration is common in mice that have multiple transgene copies.
B. burgdorferi infection was more common in mouse-fed ticks than in ticks collected from vegetation, whereas the agent of HGE was half as common in mouse-fed ticks as in ticks collected from vegetation.
Most common in mice are trichomonads, like Tritrichomonas muris.
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