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Exact(8)
Boards were re-graded from B Common, Construction Common or Construction Heart grades to either Clear All Heart or Clear Common grades (Table 7).
The most common grades 3 4 nonhematologic toxicities were diarrhea (17.1%), anorexia/nausea/vomiting (11.4%), and mucositis (8.5%).
The most common grades 3 and 4 AEs were proteinuria (11%), neutropaenia (8%), hypertension (5%), diarrhoea (5%), anorexia (5%), abdominal pain (5%) and AST/ALT elevation (5%).
The most common grades 3 4 non-haematological toxicities were asthenia (16.7%), hypokalemia (12.5%), vomiting (8.3%), stomatitis (4.2%), and diarrhoea (4.2%).
In the three-weekly cohort (n = 43), common grades 1 and 2 short-lived chills (71%%) and one grade 3 drug-related toxicity were observed [ 62].
The most common grades 3 and 4 adverse events were dyspnea (8%), hyponatremia (8%), pulmonary embolism (4%), and arthralgia (4%) [ 42].
Similar(52)
Most common grade 3 4 toxicities were neutropenia (62%), neutropenic fever (22%), and diarrhea (32%).
The most common grade 3 adverse events in the combination arm included neutropenia, leukopenia, anemia and neutropenic fever.
The most common grade 3 or higher toxicity was neutropenia (45.9%), and thrombocytopenia was observed in 13.5% of patients.
The most common grade 3/4 toxicities, occurring in = 10% of patients, included neutropenia (21%), pulmonary toxicity (12%), and hyperglycemia (10%).
The most common grade 3 and 4 nonhematologic adverse events were neutropenic fever (25%), nausea (18.8%), and mucositis (9.4%).
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