SCOP groups related domains with high identities into a family and into superfamilies, those proteins with evolutionary features dictated by common features of structure, function and sequence.
Our findings suggest that defective autophagy and consequent p62 accumulation are common features of loss-of-function mutations of the three known CCM genes.
There is a preferential involvement of the hippocampus in both low-level inorganic Pb2+ and organolead exposure, and the clinical syndromes of irritability, hyperactivity, aggression, and seizures are common features of disturbed hippocampal function.
Interestingly, in the rat, expression is observed in the EPN and intercalated cells, but only scarcely in the LA and BA [33], indicating that a common feature of NPS function in these species may be related to the modulation of EPN-mediated input to the LA/BA and its output towards the central amygdala.
Interestingly, in contrast to the regulation of cytokinin signalling, which represents a common feature of HEC function in both SAM and gynoecium, the control of auxin distribution seems to be specific for reproductive development.
This emphasizes a common feature of PFC function; that behavioral context often influences the type of information encoded to facilitate flexible behavior (Kennerley & Wallis, 2009c; Miller & Cohen, 2001; Rainer, Asaad, & Miller, 1998; Wallis & Kennerley, 2010).
Trans-repression and transmission of an epigenetic state has been observed not only in Drosophila (Henikoff and Dreesen 1989), but also plants (reviewed in Chandler 2007) and mammals (Rassoulzadegan et al. 2002), so epigenetic trans-repression may be a common feature of genome function.
Predation and sporulation are common features of previously characterized myxobacteria and these functions were used as defining traits for the taxon [32].
These common features of S. minutum minicircle CNS suggest that it functions as the origin of replication (Zhang et al. 2002).
To this end, we analysed lethality and motor function deterioration, both of which are common features of Drosophila models of neurodegenerative diseases (21– 21).
