Sentence examples for common alterations from inspiring English sources

On the other hand, still only little is known about commonly altered genes, shared molecular subtypes, common alterations in signaling or metabolic pathways, or activities of major transcriptional regulators.

Our results suggest that common alterations in single DNA repair genes are not major determinants of lung cancer susceptibility among smokers.

Common alterations of the signal transducing network seem to represent molecular hallmarks of cutaneous melanomas and therefore should continue to strongly stimulate design and testing of targeted molecular interventions.

However, HAS still tolerates common alterations in small differential ranges.

Besides these common alterations, a C107U or C109U mutation appeared independently in two virus progenies.

Other common alterations were the increase in Bacteroidetes (seven subjects), Parabacteroides distasonis (seven subjects), and Bifidobacterium adolescentis (six subjects) through RS4, and the increase of Eubacterium rectale through RS2 (eight subjects).

Analysis of the general overview of the global changes in gene expression in response to drought for the tolerant and susceptible landraces shows that there are several common alterations, albeit to a significantly different degree in terms of the number of transcripts differentially expressed and in the expression levels of genes involved in different metabolic and cellular processes (Figure 4).

Common alterations included MYC overexpression and P53 stabilization.

Overexpression and amplification of growth factor receptors are common alterations observed in HBC cells.

Enlarged terminal duct lobular units (TDLUs) are common alterations in the adult female human breast.

Allelic loss at 18q21.1 and mutations of SMAD4 are common alterations in colorectal cancer [ 26].