Sentence examples for common aberrations from inspiring English sources

Alterations of chromosome 11 were observed as the only common aberrations.

A number of these chromosomal changes appeared to reflect the common aberrations we had previously reported by karyotype analysis [1].

Classical cytogenetics by standard karyotype analysis and additional interphase FISH were performed to screen for most common aberrations using Chromoprobe Multiprobe® - CLL System (Cytocell, Amplitech, Compiegne, France).

While some of these chromosomal changes appeared to reflect the common aberrations we previously reported by karyotype analysis [1], direct comparisons cannot easily be made, since karyotype analyses are described as the frequency of chromosomal changes on a cell to cell basis, while microarray data are generated from the mixture of DNAs from the multiple cell clones that populate the cell line.

Another possibility is that within this generally high grade serous ovarian cancer cohort, the overall consistency of the common aberrations may mean that there is little "dynamic range" to detect differences associated with copy number, and that variance in outcome may have more to do with constitutive factors specific to the individual such as their immune system or pharmacogenomics.

Fusion genes are common aberrations in cancer.

To delineate the functional outcome of chromosome 8p loss of heterozygosity (LOH), a common aberration in breast cancer, we modeled 8p LOH using TALEN-based genomic engineering.

The most common aberration observed in chromosome 20 was deletion of the short arm.

The most common aberration was monosomy 14, which was observed in 17.6% (16/91) solely in nonhyperdiploid cases (P < 0.001).

The most common aberration in prostate cancers was a gain of chromosome 8 (57%), with numerical aberration of chromosome 7 being the second most frequent anomaly (50%).

Loss of 8p is a common aberration in breast tumors, and several loci on 8p have been suggested to harbor tumor-suppressor genes [ 62].