Sentence examples for committed to death from inspiring English sources

These results suggest that the MPT plays an important role in the regulation of mitochondrial cyt c release and that this may be a critical point in the apoptotic pathway in which cells are irreversibly committed to death.

Those cells failing to be selected by their antigen affinity should be committed to death.

However, when alterations are too numerous or too severe, cells are committed to death and eliminated.

Both pathways ultimately activate a cascade of cysteine proteases (caspases) and cells are committed to death thereby terminating immune responses.

In addition, if the temperature surpasses a duration or intensity threshold, the cell is committed to death, via activation of the mitochondrial pathway of apoptosis [38].

To detect cells committed to death, we used the 'In situ Cell Death Detection Kit, Fluorescein' (Cod 11684795910, Roche) following manufacturer's recommendations.

Recently, mounting evidences suggest that cancer cells can commit to death by various non-apoptotic pathways such as autophagy, mitotic catastrophe and accelerated senescence.

These results, along with caspase-independent induction of cell death and the observation that melanoma cells instantly became positive for PI along with Annexin V when committing to death, suggest that the combination of SAHA and PLX4720 may primarily induce necrosis in melanoma cells.

In that study we found that apoptosis accounted for only a portion of OA chondrocytes committed to cell death; OA chondrocyte death included both apoptosis and necrosis.

But in 2011, Doughty founded the Order of the Good Death (orderofthegooddeath.com), an online collective committed to returning death to contemporary American life.

Last year, the Saudi government sentenced 158 people to death, its most since 1995; obviously, the kingdom is on track to surpass that total in 2016 and remains committed to the death penalty.