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The performance of optimized signatures was validated by "leave-one-out" cross validation within the training set firstly, then with the validation set [14].
Electronic signatures are validated by the signer and provide the same legal binding as a handwritten signature.
The HDAC1 signature was validated by showing significantly lower predicted HDAC1 activity in cells with HDAC1 siRNA knockdown in GSE12438.
If enough signatures are validated by the city clerk, the petition will be presented to the City Council, which must schedule an election within 60 to 90 days from then.
The discriminatory power of antibody signatures was validated by analyzing data from two completely different cohorts of patients.
This signature can be validated by an independent testing cohort.
Thirdly, the identified very recent selection signatures were independently validated by utilizing DAF spectra heterogeneity and PCA of the large-scale GWAS data.
Each signature collected has to be validated by the local commune.
Notwithstanding the PLS-3 signature has also been thoroughly validated by tenfold CV × 5 in a balanced training set (n = 71).
The framework based segregation was further validated by checking for the presence of species-specific signatures and restriction analysis.
When you download Xcode from the Apple Developer website, the code signature is also automatically checked and validated by default as long as you have not disabled Gatekeeper.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com