Clinicians who are motivated to participate in a clinical trial by a personal relationship with the investigator(s) are less likely to recruit than those motivated by other factors [ 48], suggesting some clinicians may feel pressured to agree to trial participation by their personal acquaintance with researchers, without a having a strong commitment to the trial question or processes involved.
Within the local environment where the trial is conducted, acquiescence from those in positions of authority is insufficient; commitment to the trial is required.
Findings from this study strongly suggest that within the local environment where the trial is conducted, acquiescence from those in positions of authority is insufficient; commitment to the trial is required.
If your boss is sceptical, obtain commitment to a trial period with clear measures of success.
The placebo run-period was conducted to familiarize patients with the long-term commitment to the trial.
Schools were invited to participate in the trial with all classes in grade 5, and were sent a detailed memorandum of understanding to sign and to obtain head teachers' written commitment to the trial.
Reasons for loss to follow-up can include a change in the participants' location, withdrawal from treatment and/or loss of commitment to the trial, for example, due to complicated treatment regimens.
Moreover, capitalizing on the gratitude expressed by participants for the provision of quality health services, and creating a culture of 'active participation' and engagement may increase participants' sense of being valued and their commitment to the trial [ 21].
As we have noted above, non-surgeon clinicians lack the same power as surgeons in terms of participation in the research, as a surgeon's commitment to a trial is understood to include the necessary surgical team to perform the research.
However, stakeholders across all groups highlighted a focus on the biggest potential gains to be from improving aspects of the decision-making process such as informedness (which includes an understanding of their involvement and commitment to the trial over time) and opportunities for discussion with others.
