Sentence examples for commitment threshold from inspiring English sources
Due to delays in the United States Congress impeding the approval of IDA funding, the association's members implemented a set of policy triggers outlining the commitment threshold necessary for replenishment to take effect.
Activation timing affects the system's behavior mainly in the region where both cells are above their commitment threshold (upper right quadrant).
An opposite outcome is seen in point III, where there is competitive exclusion of one cell by another, even though both cells are above their commitment threshold.
When the cells are activated at the same time, interaction between two cells that are slightly below commitment threshold leads to their commitment (See Additional file 1).
Point I represents cooperation, where Cell1 that is already above commitment threshold, benefits from the presence of a sub-threshold Cell2, and consequently obtains higher levels of B. Point II represents a case of stronger cooperation, whereby Cell1 is originally below its commitment threshold, but becomes strongly committed in the presence of a sub-threshold Cell2.
As described above, the commitment threshold of Cell2 is shifted towards higher m values in the presence of the other cell, thus it will need a stronger TCR stimulation in order to exceed its threshold.
Though countries intended for the triggers to hold the United States to its commitments, the threshold ultimately provided the United States a de facto veto power over replenishment and capital increase negotiations due to its ability to bring replenishment negotiations to an impasse by threatening to withhold support.
Taken together, our results indicate that even though reduced levels of CENP-A in undifferentiated hPSCs is sufficient to support a basic centromeric mark, the switch to lineage commitment increases the threshold of CENP-A required to maintain the centromeric mark and cells with depleted CENP-A undergo G2/M arrest and apoptosis.
As recently summarized by Shenoy and Blelloch, miRNAs seem to inhibit lineage suppressors to lower the threshold for commitment.
