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Our simulations show that when cell division controlled by two independent characteristic times (one before and one after the commitment point), it is far more efficient than if cells are committed to divide within a fixed period after sensing a signal.
The ribozyme forms much of its tertiary structure significantly faster than it reaches this commitment point and the tertiary structure is expected to be stable, suggesting that the commitment to fold along pathways to the native or misfolded states is made from a partially structured intermediate.
In addition a diversion into work with budding and fission yeasts led to work on tyrosine phosphorylation and dual specific kinases in budding yeast and the demonstration that the Cdc18 protein of fission yeast couples S-phase to mitosis and to the cell-cycle commitment point, Start.
So, from a commitment point of view, we're looking at 20 hours annually.
Critics of the growing troop commitment point out that al Qa'ida is largely absent from Afghanistan, having found refuge in neighboring Pakistan.
In budding yeast, Cdc48 is required for passing Start, the cell cycle commitment point in G1, by degrading the G1-cyclin-dependent kinase inhibitor Far1 [14].
Similar(38)
Their commitment points to the value attached to examination success.
It meant keeping my energy, talents and commitment pointed in the direction I wanted to go.
Suicide could indicate a higher level of commitment and point to the existence within Britain of extremists willing to die for a cause.
The government has a manifesto commitment, ministers point out, to turf them out.
Labour speaks of this as a "commitment", they point out, while Conservative politicians refer to it only as an "aspiration".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com