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Similar to WNT3A, these Wnt agonists elicit a characteristic β-catenin signalling response in a FZD-selective fashion, enhance the osteogenic lineage commitment of primary mouse and human mesenchymal stem cells, and support the growth of a broad range of primary human organoid cultures.
"I was most struck by the high dedication and commitment of primary healthcare workers during polio campaign in the most isolated areas, in a very remote villages" - says Nisso Kasymova, UNICEF's HIV/AIDS Coordinator.
TGFβ1 and the related family of bone morphogenetic proteins were reported to promote commitment of primary rat neural crest stem cells to autonomic neuronal lineages and smooth muscle-like cells in vitro (16, 51).
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Several important factors that determine myogenic commitment of the primary muscle cells were characterized by quantitative real-time RT-PCR and immunofluorescence.
The Convention also implemented the Revolution's long-standing commitment to primary education with a system of free public primary schooling for both boys and girls.
But nonprofits needn't rely on the commitment of volunteers whose primary goal is to return to full-time work.
The primary commitment of the LHCb collaboration is the study of particle antiparticle asymmetries and of rare decays of particles containing b and c quarks.
For staff members exempt from governmental regulations regarding compensation for overtime work: Acceptance of employment, consulting, public service, or pro bono work which can result in conflicts or the appearance of conflicts with a staff member's primary commitment of time and energy to the University.
The commitment of India's elite towards primary education, especially in rural areas, is bordering on scandalous neglect; funding goes towards supporting tertiary education at the expense of millions of poor children.Murali ReddyLake Hiawatha, New JerseyJob titlesSIR – I agree that "spelling errors undermine" Paddy Ashdown's "authoritative tone" on peacekeeping ("Paddy's passions", June 30th).
In this context the Eurogroup welcomes the commitment of Greece to maintain a primary surplus of 3.5% of GDP until 2022 and, thereafter to continue to ensure that its fiscal commitments are in line with the EU fiscal framework.
We were also able to analyze the apparent relative expression levels (based on EST abundance) of genes governing the commitment of carbon flux into several primary and specialized metabolic pathways in different tissues (Table 1), as we have previously done for glandular trichomes [ 19].
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