Sentence examples for commitment of differentiating from inspiring English sources

Commitment of differentiating embryonic stem cells (ESCs) toward the various lineages is influenced by many factors, including androgens.

The imposition of lineage commitment on differentiating pluripotent cells in culture has been a long-term challenge for ES cell biologists.

Hence, the first division of differentiating hESCs sometimes yields daughters with diverging fates, with implications for the efficiency of directed differentiation protocols and the underlying rules of lineage commitment.

A problem of differentiating one from another? A. Yes.

Commitment to differentiate into specific lineages requires strict control of gene expression to coordinate the downregulation of lineage inappropriate genes while enabling the expression of lineage-specific genes.

Indeed, MEK inhibition on normal stem cells (induced pluripotent stem cells and embryonic stem cells) maintains self-replication of the pluripotent state and inhibits their commitment to differentiate.

Next, we examined whether culture of EBs in a low oxygen environment affected their commitment to differentiate into a specific lineage.

We honor that commitment, to differentiate our relationship, no matter what.

Abnormal EVI-1 expression probably contributes to AML by interfering with other genes controlling the commitment to differentiate.

The regulation of the commitment to differentiate to several cell lineages is currently an area of intense research interest.

Studies of p21Waf1/CIP1 null mouse keratinocytes indicated that the induction of p21Waf1/CIP1 in early differentiation is required for initial commitment of keratinocytes to differentiate [9], [10].