Crucially, this commitment was supported by the international community with a strong political imperative, technical assistance, and substantial funding [ 1].
This nuanced commitment to engagement is supported by answers to some of Chatham House's more detailed questions.
George McClendon, dean of the College of Arts and Sciences at Duke University and former chair of the chemistry department at Princeton, says that even top research institutions are "first and foremost teaching institutions and are looking for a commitment to teaching which is supported by the commitment to research which keeps that teaching at the cutting edge".
"Our absolute commitment to the NHS is supported by a strong economy so that it's there, free at the point of use, for the future, able to cope with an ageing population, and able to offer the best healthcare in the world".
The notion that TFH-cell commitment can start early is supported by the observation that Bcl-6 expression can be detectable in antigen-specific CD4+ T cells already during DC priming within 2 days after immune challenge (Choi et al, 2011).
A source said: "We asked them to write these commitments in a way that is supported by the behavioural literature, making the commitments specific, including a 'how', 'what', and a 'when'".
Looking beyond Italy, he said, "If lasting stability is to be given to the new unity of Europe, there must be a commitment to ensuring that it is supported on those ethical foundations which were once its basis".
The government's high level of involvement is supported by political commitment and resourcing.
An alternative explanation, namely back recruitment of cells in early lineage commitment, could not be supported experimentally as transduction of differentiated EpCam+ CD49− luminal cells with lenti- ZNF703 did not induce colony formation in this population (data not shown).
