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He was also courageous (or naïve) enough to commit single-handedly to the enormous task ahead, starting with a blank page on which he created a novel view of the inter-workings of the cell".
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Few studios will single-handedly commit to a high budget of $70m or above – slate financing deals exist to preclude that eventuality, so the studios can share the risk on a big bet, even if it does star Brad Pitt.
As everyone knows, our former Vice President has single-handedly committed himself to fighting global warming.
Kentucky lawmakers are so committed to tobacco that former Senator Jim Bunning once single-handedly held up President Obama's nominee for deputy U.S. trade representative because he was angry at Canada for banning the sale of candy-flavored cigarettes.
Almost single-handedly, O'Connor rewrote abortion law.
You single-handedly changed cricket.
He did not modernize basketball single-handedly, just one-handedly.
We have rebuilt China single-handedly.
Jack Kerouac single-handedly made Cadillacs cool.
It did not single-handedly rebuild Western Europe.
He did not do it single-handedly.
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