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They are also filled with conservative and commercially safe works at estimates that are meant to entice collectors.
Off-Broadway plays, usually produced on low budgets in small theatres, have tended to be freer in style and more imaginative than those on Broadway, where high production costs often oblige producers to rely on commercially safe attractions to the neglect of the more serious or experimental drama.
In fact they are perfectly happy and capable of playing within the parameters of radio friendly and commercially safe pop rock.
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Long before that, many newspaper owners in America had concluded that it was commercially safer to avoid testing the sensitivities of readers—and advertisers by giving editorial cartoonists free rein.
In 1995, she ventured into the more lighthearted, and commercially safer, reaches of family comedy by acting in the Disney remake of The Parent Trap, achieving the feat of not being upstaged in what is essentially a vehicle for a juvenile performer, with Lindsay Lohan in the role that in 1961 had been taken by Hayley Mills.
They are also used commercially as safe food, feed and cosmetic colorants and they protect plants from photooxidative stress.
For those observing Monday's event with their own telescope, NASA offers these important safety tips: "Use only a commercially available safe solar filter covering the sky-end of a telescope or both sky-ends of a pair of high power binoculars to observe the transit.
While Toy Story 3 is, by the studio's own standards, a safe bet at the box office, the more commercially secure Pixar has become, the more it has used its bankability as a springboard for innovation and experimentation.
But commercially good?
Although there is still a role for assessment of innovative medical treatment using unproven stem cell interventions - like the initial 1957 hematopoietic and 1981 skin stem cell grafts - this approach should be considered as a 'one-off' and not offered widely or commercially until proven safe and effective.
keep it clean, if you prune an infected plant with a pair of pruners, either sterilize the pruners with bleach and water, a commercially available sterilizer safe for plants, or flame the tool to kill the disease pathogen before you prune a healthy plant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com