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But the researcher warned that it remained unclear whether such devices "can really compete against other commercial pathways that can take CO2 and hydrogen to various products".
Using the commercial pathways knowledge database Ingenuity Pathways Analysis (IPA), we identified canonical pathways that were enriched or over-represented in the common metastatic signature [ 45].
We use See5 as a rule induction method (Rulequest, St. Ives, Australia) and MetaCore, a commercial pathways database with analysis tool distributed by GeneGo (St. Joseph, MI) [ 32] for implementation of the BCRI strategy for network discovery [ 11- 13].
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While ATP required applicants to submit a plan containing a commercial pathway and identify potential markets, it is also understood that the very nature of the technology R&D undertaken may not result in commercializable products/processes until several years after project completion, but awardees are expected to pursue commercial avenues as soon as feasible.
We evaluated the phosphorylation levels of key transcription factors in tOASFs using a commercial pathway scan kit.
This gene set was collected from commercial pathway panels, public domain resources such as Pathway Commons (http://www.pathwaycommons.org) or relevant literature [Zhang, J.D., manuscript in preparation].
Using a commercial pathway scan kit and western blotting (Supplementary Figure S2), the activation levels of inflammatory-associated key intracellular signaling proteins in tOASFs were evaluated.
There is a pressing need for a genuine collaborative and interdisciplinary effort, spanning from fundamental academic research to the commercial pathway towards translational biomedical technology.
The HRneg/Tneg gene signature was prognostically compared with eight other previously reported gene signatures, and evaluated for cancer network associations by two commercial pathway analysis programs.
These pathway-oriented interaction networks can be obtained from freely accessible pathway repositories (Table 1) and from commercial pathway databases such as Ingenuity Pathways Analysis (IPA, Ingenuity), MetaCore (GeneGo) and Pathway Studio (Ariadne).
While a number of commercial pathway knowledge bases are available for performing traditional pathway analysis [ 10], the costs, format, data sharing restrictions, and terms of use make these less attractive as a source of data for network extraction.
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