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Three reviewers provided strengthening comments to manuscript.
PK and SM enrolled patients, performed interventions and made final comments to manuscript.
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We also thank Anu Korosuo, Matteo Vizzari, Ariane De Dominicis and three anonymous reviewers for constructive comments to the manuscript.
Brian van Wilgen contributed valuable comments to the manuscript.
Paul Gignac offered useful comments to the manuscript.
We thank Jose I. Pueyo for unpublished results and comments to the manuscript.
H.L. and I.S.K. thank Dr. Alvin Kho for his comments to the manuscript.
We wish to thank two anonymous reviewers for their constructive comments to the manuscript and Amber Hardison for linguistic remarks.
The authors would like to thank the editor M. Baylis for very helpful comments to this manuscript.
We thank Nigel Franks, Ana Sendova-Franks and Raphael Jeanson, for useful discussions and comments to the manuscript.
We thank Drs P. Roche and P. Cresswell for comments to the manuscript and Dr. G. Moldenhauer for antibodies.
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