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The magnitude of change was similar for girls and boys, although boys commenced the trial with a lower median ISI (1.2 [range 0.3 to 3.0]) compared to girls (1.4 [0.3 to 3.4]), P = 0.04.
After adjusting for pubertal stage, the magnitude of change was similar for boys and girls, however, boys commenced the trial with a lower total body fat percentage (46.3% ± 5.3) compared to girls (50.7% ±5.3), P < 0.001.
The magnitude of change in both SBP z-score and DBP z-score over the 12 months was similar for boys and girls, although boys commenced the trial with a higher blood pressure.
The magnitude of change (estimated mean difference 6.8%[955% CI: 4.9 to 8.8]) over the 12 months was similar for boys and girls, although boys commenced the trial with a higher mean (±SD) BMI%95th centile compared to girls; 136.8 ± 21.1 and 129.3 ± 20.6, P = 0.020, respectively.
Similar(56)
When Jackson commenced the trials he made a speech, and this is what he said in his opening: "We must never forget that the record on which we judge these defendants today is a record on which history will judge us tomorrow.
"Commencing the trial date in 2007 will not result in any prejudice to any other party".
Before commencing the trial, ethical approval was obtained from the University of Manchester.
In retrospect, we should have conducted a pilot or feasibility study before commencing the trial.
The first author (YHK) performed the TKAs using the Medial Pivot prosthesis in 15 cases before commencing the trial.
The 17 participants who were randomised but did not commence the trial were included in this analysis.
I wonder if Kim et al. could describe their experience using the Medial Pivot replacement before commencing the trial.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com