Sentence examples for commence a phase from inspiring English sources

When doctors commence a Phase I study, they generally have evidence to believe a particular drug will be of benefit.

Advanced Cancer Therapeutics has recently gained FDA approval to commence a phase I clinical trial (NCT02044861) to test the safety of a small-molecule PFKFB3 inhibitor called PFK158 in patients with advanced solid tumours.

However, to our knowledge, there is no prospective clinical trial evaluating combination treatment of any substance with carbon ion therapy, hence we will shortly commence a phase-II trial with the EGFR-receptor antibody cetuximab addressing this issue [ 26].

We have now commenced a Phase II trial to further evaluate response rates.

The patient commenced a Phase III Canvaxin or Cancer Vax (C-Vax) trial for resected stage III melanoma in 2002; however, in June 2002, a solitary left cerebellar metastasis developed.

Few recent AD programs have followed this model, with sponsors tending to commence a full phase III program after seeing evidence of target engagement biochemically in smaller phase II studies.

The court will then commence a sentencing phase, where Roof has indicated he will represent himself, making it more likely, experts say, that he will be sentenced to death.

We have commenced a multi-phase project to experimentally measure the power and energy of a 1 16-scale tunneling vehicle.

Nevertheless, this small decline in the recent population size reveals a commencing phase of a bottleneck in C. kanehirae inflicted by anthropogenic factors.

The clinical development of antisense ONs (AONs) commenced in the early 1990s with a phase I trial using AONs directed against p53 transcripts in patients with either relapsed or refractory acute myelogenous leukemia or myelodysplastic syndrome.

From results obtained in these studies, in January 2014, a Phase I clinical trial commenced, as it will be mentioned in Section 5 of this review.