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However, using such studies comes with methodological challenges, such as the potentially inadequate measurement of back pain when compared with more focused studies [ 106].
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Each comes with its own methodological challenges, and existing approaches and tools to do so can be costly to implement or require considerable technical knowledge and skill.
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The role comes with unique challenges.
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This opportunity comes with big challenges for weak health systems.
However, putting this into practice comes with some challenges.
It is true that this approach, too, comes with serious methodological caveats, such as verifiability, selection bias or observer bias.
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Like then, the opportunity comes with challenges.
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