Later, as prison-based experiments came under considerable critique, clinical research was moved into private medical centers and contract research organizations.
Since its adoption, however, the 2000 definition has also come under considerable criticism.
The Food and Drug Administration uses a different measurement, and it has come under considerable criticism from activist groups like the Mercury Policy Project.
Mr. Penny, who had been expected to run, had come under considerable criticism from party members who viewed him as too conservative.
It has come under considerable criticism from members of Congress who say that it will lead to higher fares and diminished service.
Mr. Patten has come under considerable criticism for the large severance given to Mr. Thompson's successor, George Entwistle, who lasted only 54 days in the job.
Icann has come under considerable criticism over its decision to open up the domain-name assigning process.
The state constitution had come under considerable criticism beginning in the 1840s because it allowed most government positions to be filled by appointment.
Lee had come under considerable criticism for the way his department handled the investigation, and stepped down from his post last week following a no-confidence vote from the city commission.
