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There is also a need to evaluate potential combinations of prognostic tools and biomarkers and their combined predictive value in determining NHAP severity and outcomes.
In conclusion, the combined predictive value of differentially expressed genes in peripheral blood correlates with the extent of coronary atherosclerosis.
To estimate the combined predictive value of these two miRs, with and without PSA, we formed support vector machine classification models using a linear kernel.
In this way the unique and combined predictive value of the current and lifetime maternal depression and anxiety problems on both difference scores could be assessed.
‡The original paper mentions several polymorphisms per gene and that one for each gene was included to assess the combined predictive value of six variants.
Thus, future studies should focus on determining the combined predictive value of oliguria, clinical variables, standard urinary biochemistry, and novel biomarkers in the early diagnosis of AKI [ 40, 43].
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The question is not only whether certain measures have superior prognostic value but also whether they contribute independent information such that, when combined, their predictive value is additive.
When the TDR and urinary DiAcSPM were inversely combined, the predictive value of non-invasive tumor was 94.9% (37 of 39).
A panel of four genes that included p16, DAPK, PAX5 β, and GATA5 was methylated in 77% of tumours and had a combined positive predictive value of 86%.
Combined, the predictive value was improved with a change in BNP concentration of <46% at discharge with an absolute BNP concentration of >300 pg/ml giving an odds ratio for adverse events of 9.61.
The key feature of the obtained reduced model is that it combines high predictive value (all state variables keep their biological interpretation) with very low computation time.
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