The aim of this study was to develop shorter AMP fragments that combine maximal bactericidal effect with minimal synthesis cost.
It was hypothesised that the VL ALT perforator flap would offer adequate tissue volume combining maximal freedom in planning with minimal donor site morbidity.
However, they measured PCEF immediately after extubation and enhanced performance by combining maximal insufflation with an abdominal thrust timed to glottis opening.
Equal gain combining, maximal ratio combining, orthogonality restoring combining, and minimum mean square error techniques are some versions of linear equalization employed in MC-CDMA, where appropriate coefficients are used as weighting factors for the signals from different subcarriers.
Following the paradigm of "precision medicine", contemporary urologic surgery has entered a technology-driven era of "precision surgery", which entails a range of surgical procedures tailored to combine maximal treatment efficacy with minimal impact on patient function and health related quality of life.
Considering this fact, a novel immunotherapy combining maximal efficacy and minimal side effects seeks to alter these inflammatory responses for treatment or prevention of the disease.
The classical therapeutic sequence combines maximal debulking surgery followed by adjuvant platinum and paclitaxel-based chemotherapy (Bristow et al, 2002; International Collaborative Ovarian Neoplasm Group, 2002; Ozols et al, 2003; Cannistra, 2004).
We were able to achieve minimum values of StO2 below 10% by combining maximal exercise and arterial occlusion fast enough to allow multiple measurements.
Despite a multimodal therapeutic approach combining maximal cytoreductive surgery with fractionated radiotherapy and alkylating temozolomide chemotherapy, prognosis remains dismal: median survival of patients is 14.6 months, with a 2-year survival rate of 27.2% (Stupp et al, 2009).
More recently, long-term survivors including patients with recurrent and disseminated disease have been reported, and disease-specific protocols and registries combining maximal surgical resection, intensive chemotherapy with or without stem cell support, and radiotherapy have been opened and show encouraging, albeit preliminary results 17191719
