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Gene expression control results from the combined interactions of the nearly hundred proteins forming the pre-initiation complex, thousands of transcription regulators, and genomic DNA.
We propose that the combined interactions of S4, S17, and S20 with different helical junctions bias the free-energy landscape toward a few RNA conformations that are competent to add the secondary assembly protein S16 in the next step of assembly.
The D2 iris disease is initiated by the combined interactions of the Tyrp1 b and Gpnmb R150X mutations [ 22, 23].
This is presumably due to the combined interactions of environmental toxicants with the endogenous unsaturated aldehydes (e.g., acrolein, 4-hydroxy-2-nonenal) and oxoaldehydes (e.g., glyoxal, methylglyoxal) generated during oxidative stress.
To the best of our knowledge, no other groups study the combined interactions of endothelial cells and platelets in this pseudo-co-culture system and no groups have investigated how sidestream tobacco smoke can accelerate or decelerate cardiovascular pathologies during diabetic vascular conditions.
While membrane anchoring firmly restricts LRP4 to the two-dimensional surface of the muscle fiber and thereby ensures its continued presence in the MuSK/agrin/APP/APLP2 signaling complex, the loss of the transmembrane segment can be partially compensated for by the combined interactions of APP, APLP2, MuSK and agrin with the LRP4 ECD.
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This confusion may, in part, be because symptoms result from the combined interaction of many genes and these interacting genes are associated with specific sub-phenotypes of schizophrenia rather than schizophrenia as a whole.
The primary film may be a complicated solid phase resulting from combined interaction of LiAlCl4, SOCl2 and catalytic carbon surface.
A three variable Box and Behnken factorial design (Table 1) was used to study the combined interaction of these factors on various properties of yarn and fabric.
Corrosion fatigue in metals is presented as the result of the combined interaction of mechanical stress and stress-corrosion velocity caused by the aggressive environment.
Fig. 4 Combined interaction of diphenyl-N- trichloroacetyl -amidophosphate (HL) andiphenyl-N- trichloroacetyl -amidophosphateversions): a, b bindiphenyl-N- trichloroacetyl -amidophosphateercalation into minor andiphenyl-N- trichloroacetyl -amidophosphate
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