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The safety of the drug combination was explored with the 3-weekly dose of paclitaxel 175 mg m−2 combined initially with 2.5 mg of everolimus daily (dose level 1) and then escalated to 5 mg daily (dose level 2) and 10 mg daily (dose level 3).
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The combined company, initially named Allied-Signal, was renamed AlliedSignal in 1993 to indicate the full integration of its business units.
The notion to scrap the super combined was initially raised last season but resurfaced at meetings last month at which World Cup ski racing's governing body discussed eliminating the event over the next few years.
For example, when water and sugar are combined, they initially form a homogenous union.
Combined Operations initially suggested the men should fight their way to the Swedish border, but MI9 believed their chances of survival were better if they attempted to disguise themselves at Norwegians and travel in pairs.
SNP and microsatellite data were combined and initially assembled into linkage groups according to their predicted physical genome locations.
In all other cases, management combined surgery (initially for localised forms, n=58, or after neoadjuvant treatment, n=11) and/or radiotherapy and/or chemotherapy (Table 1).
Associations between client/service characteristics and the provision of each form of care (assessment, brief advice and an offer of referral/follow-up for each individual risk and for all risks combined) were initially analyzed using chi-square analysis.
The Brief Negotiation Interview (BNI) and Emergency Department-Initiated Buprenorphine/Naloxone for Moderate/Severe Opioid Use Disorder is a screening and brief intervention and referral to treatment (SBIRT) model that was developed initially combined with ED-initiated buprenorphine treatment.
Over the past 15 years, both Internet stocks and houses have demonstrated the extraordinary excesses that can be created by combining an initially sensible thesis with well-publicized rising prices.
Recipes commonly call for the flavorings only added at the end, but combining them initially may be fine too.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com