The combined results implicate USP7 in the regulation of PML-NBs.
Thus, the combined results implicate an important role of the lysosome in TFEB-mediated pTau clearance.
Our combined results implicate host population size as a key factor that shapes the evolutionary trajectories of naturally occurring ΔmtDNA elements.
Combined, these results implicate oxidative stress and response as contributing factors in the acute galactose sensitivity of GALT-null Drosophila and, by extension, suggest that reactive oxygen species might also contribute to the acute pathophysiology in classic galactosemia.
In contrast to viral neuraminidase, bacterial neuraminidase has not been implicated in combined viral/bacterial pneumonia or post-influenza pneumonia [ 34, 37, 40].
Together, these results implicate a combined role for both purifying selection and genetic code optimization, in facilitating the coexistence of structural with genetic information.
Combined, these data strongly implicate the 4 bp 5′ deletion as a causal mutation in Duarte galactosemia and suggest that direct tests for this deletion, as proposed here, could enhance or supplant current tests, which define D2 alleles on the basis of the presence and absence of linked coding sequence polymorphisms.
It would be helpful to combine the evidence implicating association at the level of the whole gene rather than just for individual markers or haplotypes.
Those accounts, combined with intelligence reports that implicated Mr. Kim in the bombing of a South Korean airliner and other terrorist acts, encouraged the impression that Mr. Kim was somehow dissolute and, perhaps, a little unstable.
In keeping with this, combined administration modulates brain activations implicated in appetite control to an extent similar to that observed physiologically after a meal.
