Sentence examples for combined activation of from inspiring English sources
After stimulation with type I collagen, β1 integrin activates Gli-1 whereas DDR1 activation stimulates the extracellular regulated kinase; combined activation of these two proteins enhances Bmi-1, which drives cell proliferation (Suh and Han, 2011).
Holland, E. C. et al. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice.
Subsequently, the combined activation of pre-B cell antigen receptor signaling pathways and attenuation of IL-7R signaling in small resting pre-B cells dramatically modifies the transcription factor landscape, supporting the induction of monoallelic Igκ gene rearrangements.
Subsequent trials will validate the efficacy of BIM-065 for the treatment of acromegaly and other potential indications that may be amenable to treatment through combined activation of SST and DA receptors.
Since their stimulation may modulate the nervous signaling altered by neuropathies, the purpose of the present research is the study of the combined activation of 5‐HT1A and α2 receptors by rationally designed imidazoline ligands ((S --1 and 2–5) in a rat model of neuropathic pain (chronic conS --1tion injury - CCI).
First, a combined activation of group I mGluRs (mGluR1 and mGluR5) induces a transient depression that is cannabinoid 1 receptor dependent.
It appears that different populations of SPNs specifically control different aspects of locomotor behaviors, and combined activations of these populations would generate various types of behaviors.
Blood compatibility of TiO2 nanotubes (TNTs) has been assessed in rabbit platelet-rich plasma (PRP), which combines activation of both blood plasma coagulation and platelets.
Therefore, researchers are designing peptides that combine activation of the glucagon receptor with further incretin properties, which will treat obesity while mitigating the hyperglycaemic effects of glucagon.
We show here that intratumoral (IT) treatment with lipopolysaccharide (LPS), a TLR-4 agonist, significantly enhanced the local therapy induced by VSV by combining activation of different innate immune pathways.
Figure 6 (lower part) illustrates with a very simple example the way in which the probability of combined activation can be used to calculate the probability of activation (signal transmission) of a circuit.
