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19 Within each meta-analysis we used DerSimonian and Laird random effects models to combine intervention effects across trials.
In addition, other aspects relevant to the review might change, such as ideas about the cause of the illness, ways of dealing with any adverse effects of the intervention, changes to the methodology used to combine intervention effects, or other aspects of health care relevant to people making decisions about the intervention.
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Studies that combine interventions have, however, been more successful [ 12].
These meta-analyses may also combine interventions that are, in practice, implemented in a variety of ways.
Compared to physical exercise, combined intervention produced greater effects on overall effect size (0.22, p < 0.01), while no significant difference was found between combined intervention and cognitive intervention.
The findings suggest that combined intervention demonstrates advantages over control group and physical exercise, while evidence is still lacking for superiority when compared combined intervention to cognitive intervention.
WM measurements did not show significant differences between the two groups: WM and combined intervention.
This meta-analysis aimed at assessing the efficacy of combined intervention on cognition by comparing combined intervention to control group, cognitive intervention and physical exercise.
Effects of combined intervention were moderated by age of participants, intervention frequency and setting.
The first approach consisted of a combined intervention in text production and WM while the second focused only on WM.
We followed Cochrane Collaboration guidance and combined intervention and control groups to create single pair wise comparisons.
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