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Wavelet transforms were used to combine expression values of neighboring reactions by all possible combinations of subtractions and additions.
First, it has introduced doublets, a novel method to combine expression data from gene pairs.
Furthermore, the use of bi-directional promoters can be used to combine expression of two independent genes as demonstrated in this study.
Therefore, to generate a more comprehensive yet concise view of Wnt signaling activity in IPF, we sought to combine expression and localization analysis of Wnt signaling components, paired with phosphorylation analysis of Lrp6 and Gsk-3β, together with quantitative expression analysis of Wnt target genes.
This approach allows to easily combine expression information with genomic context information.
These methods often combine expression and protein-DNA interaction data to recover the underlying networks.
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We combined expression profiling and bioinformatics and analysed metabolic pathways enriched with differentially expressed mRNAs and mRNAs which are known to be validated targets of differentially expressed miRNAs.
Ki-67-labeling index of combined p53+/mdm2+ expression cases was significantly higher than those that lacked combined expression (P =.004).
Thus, combined expression of genes encoding Fe transporters or Fe storage proteins are promising approach for Fe biofortification.
Industrial material fermentation results from yeast-RSP5-UBC4 (combinexpressioniof of ubiquitin conjugated enzyme E2 and ubiquitin ligase E3) showed a 2.4% increase in ethanol production.
Combined expression of these activities in E. coli strains optimized for the production of l-phenylalanine resulted in the first completely fermentative production of d-Phg.
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