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"We make hundreds of combinations to evaluate in order to optimize the performance of each drug," says Jeff Hrkach, senior vice president of technology research and development.
Visual stimuli were accompanied by beeps in different combinations to evaluate both fission illusion (one flash presented with a number of beeps varying between 0 and 4) and fusion illusion (2-4 flaccompaniedpanied by only one beep).
The number of combinations to evaluate is three (producing to Separator 1, producing to Separator 2, or to both) to the power of 7 (number of wells) 37 = 2187 combinations.
This article discusses various assay techniques, in vitro trails and in vivo models available, to help researchers in choosing right biological methods and its combinations to evaluate efficacy of potential drug candidate.
Standard chemicals and methods (APHA 2005) were used (1) to determine acidity of the water used in the Power Stations, (2) for preparation of simulated acidic water in the laboratory as is used in the Plants, (3) for detailed neutralization experiments with the acidic water in batch reactors with alkaline materials and in various combinations to evaluate the neutralization efficiency.
Phylogenetic methods were applied using each barcode locus taken alone and in combinations to evaluate species recovery.
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Leaf-on and leaf-off LiDAR data were used separately, as well as in combination, to evaluate the relative strength of these datasets to describe 3D canopy architecture and vertical forest structure.
They apply BSC and analytic network process (ANP) methods in combination to evaluate logistics performance indicators.
Clinical variables that remained significant in the final model were used, one-by-one or in combination, to evaluate their ability to predict exercise-test outcome.
The secondary objectives were to assess the safety and tolerability of this combination, to evaluate if there was any pharmacokinetic interaction between pertuzumab and docetaxel and to determine the objective responses in advanced solid tumours.
We performed a phase II study of a combination chemotherapy with irinotecan, leucovorin and 5-FU in metastatic gastric cancer patients, who were previously treated with taxane and cisplatin combination, to evaluate the antitumour activity and toxicity of the combination chemotherapy.
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