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Thus, almost all clinical PET systems sold within the last years are combinations of PET and computed tomography (CT) systems, integrating the strengths of both modalities: the high specificity and sensitivity of PET making already functional changes in tissues visible at a very early stage of disease and the detailed morphologic information provided by CT [ 1].
To assess whether (combinations of) PET and IHC parameters could distinguish tumor lines we created Random Forest models based on these parameters to predict tumor lines.
In previous combinations of PET and NIRF, the positron emitter and fluorophore were independently attached (4, 7), whereas 1 combines these capabilities in a single, versatile small molecule only slightly larger than the usual commercially available NIRF labels.
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Immuno-PET, the combination of PET and a radiolabelled mAb, combines the high sensitivity and resolution of a PET camera with the specificity of a mAb [ 17, 18].
Still, due to the potential advantages of a combination of PET and MRI over combined PET/CT systems, clinical PET/MRI systems are eagerly awaited.
They give a short summary of current relevant clinical applications of PET and MRI in the setting of atherosclerosis and discuss future potential vascular applications exploiting the unique combination of PET and MRI.
The combination of PET with Diffusion Weighted Imaging (DWI) is a promising application of PET/MR.
The combination of PET and MRI is valuable in several inflammatory disorders, such as myocarditis, sarcoidosis, pericarditis, and valvar infections.
The combination of PET and MRI into a hybrid device is challenging since both systems might interfere with each other.
Interestingly, pre-clinical PET/MRI developments preceded clinical developments for a combination of PET and MRI [8], unlike PET/CT or SPECT/CT.
The combination of PET and MRI often provides incremental information in the evaluation of cardiovascular diseases, more than each of the individual modalities separately.
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