Sentence examples for combinations of modification from inspiring English sources
This genetically encoded peptide-based strategy allows for rapid diversification of these natural products by mutation in the precursor genes merged with unique combinations of modification enzymes.
Stunning numbers of reversible modifications along with different combinations of modification involving physical interactions of enzymes and regulatory proteins in both directions throws insights of complexity of epigenetic regulation by histone modification (Patra and Szyf 2008; Kouzarides 2007).
Many of the identified TOMM families have an abundance of diverse precursor peptide sequences as well as unfamiliar combinations of modification enzymes, signifying a potential wealth of novel natural products on known and unknown biosynthetic scaffolds.
These biosynthetic gene clusters are predicted to produce diverse final products, and the identification of additional combinations of modification enzymes could expand the potential of combinatorial natural product biosynthesis.
The effects of various individual or combinations of modifications of SPCEs on their electrochemical sensor properties toward oxidation of NADH have been investigated by cyclic voltammetry.
Combinations of modifications are also informative about active versus poised states of these elements [ 22– 25].
Combinations of modifications are thought to constitute the so-called "histone code".
Distinct combinations of modifications defined 15 enriched chromatin states, which in turn were used to functionally annotate chromosomal regions.
As such, histone modifications and certain combinations of modifications play a major role in dictating the accessibility status of the chromatin.
