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The SLR did not reveal general superiority of such combinations in comparison with respective monotherapies.
The relative importance of each symptom and their combinations in comparison with nasal endoscopic findings were statistically analysed using ORs as a reference of no symptoms.
This concept will be applied to Phase I and II clinical trials with novel drugs or drug combinations, in comparison to pharmacokinetic analyses.
A large number of factors can be evaluated in order to quantify their relative effect on emissions, but using a reduced number of combinations in comparison with those used in an equivalent statistical factor design.
This study examined the effect of O-alkylguanine-DNA-alkyltransferase (ATase) depletion by the pseudosubstrate O-benzylguanine (BG) on the anti-tumour activity and normal tissue toxicity in mice of three such molecular combinations, in comparison with BCNU.
In our study, patients with diabetes who received metformin-only had a consistently lower risk of liver cancer compared to non-users of any anti-diabetic medications, while the risks for use of all other medications or combinations in comparison to non-use were ∼1.0.
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With the Spitzer's questionnaires a trend towards an improved quality of life index was observed during treatment with the carboplatin combination in comparison to the cisplatin combination.
Additionally, since we consider per capita gross domestic product as an indicator to economic growth while studying the Granger causality between the two (see details in Emperical strategy), the choice of insurance market density is a better combination in comparison to insurance market penetration.
31% (4/13) showed increased resistance with the combination in comparison with treosulfan alone and 1 sample showed no change.
Further studies need to investigate if there is a clinical benefit of the combination in comparison to a Docetaxel monotherapy.
At 24 hr there was no significant difference in IC50 values for the combination in comparison to sorafenib alone in both the HepG2 and LX2 cells.
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