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The design is extended in a such a way that the number of different combinations for the first step is small.
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In conclusion, the results of our trial argue strongly against the omission of platinum compounds and support the use of platinum/taxane combinations for the first-line treatment of CUP syndrome.
In addition, the combination of capecitabine and oxaliplatin is also being investigated in a phase III trial (REAL 2) in triplet combinations for the first-line treatment of gastro-oesophageal carcinoma (Sumpter et al, 2004; Tebbutt et al, 2004).
Because of the large number of LAPs, central distribution of conjugate combinations for the second run was not feasible.
Subsequently degradation of triazophos pesticide in aqueous solution (20 ppm solution of commercially available triazophos pesticide) has been investigated using hydrodynamic cavitation and ozonation operated individually and in combination for the first time.
In the meantime, many clarinetists and singers had performed the work but I had to find just the right combination for the first recording of the song.
Wellons will be the first U.S. inmate put to death since the botched execution of Clayton Lockett in Oklahoma, who died of a heart attack in April after clenching his teeth and showing distress while officials administered a new lethal drug combination for the first time.
In the abacavir-switch arm, patients received both abacavir and the hyperlipidemia-associated PI with their usual two-NRTI background combination for the first 4 weeks, after which the PI component of the regimen was discontinued.
In Figure 10a-c the scatterplot of the scores are shown for different combinations of the first three PCs, using the Attribute-Value grouping method suggested by author G.G. (based on supposed age of production).
The results of this study challenge the use of the platinum, 5-FU and cetuximab combination for the first-line treatment of recurrent and/or metastatic HNSCC.
IRI-S uses up one of promising drug combination for the second line treatment without sufficient prolongation of TTF when compared with S-1 monotherapy.
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