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Further studies are however required to enlighten most promising treatment combinations, considering evidences of limited usefulness of combining different treatments at the same time [ 35, 36, 38, 39].
As another example, Yin et al. [ 54] used three-node enzymatic motifs to study about the synergistic or antagonistic interactions within drug combinations considering different motif topologies and parameters.
The 3' end of the primer (at least 11 bases) is degenerate in a way that represents all possible nucleotide combinations considering that there are usually several codons per amino-acid.
ODE models can be interrogated to test hypotheses of cellular response to drug combinations, considering whole sets dosage permutations and used to discover optimal points of manipulation within the network [ 13, 16].
The detection of T2D causal SNP combinations considering common SNPs with low statistical power in single SNP association analysis may perform better in disease risk predictions because common SNPs can explain critical effects if they interact with other SNPs as a SNP combination.
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All bracket/archwire combinations considered were found to have play angles far above the ideal.
Using this scheme, the transition weight between two combinations considers the score of the target combination and the differences between the candidate intensities.
Table 3 gives the direct and residual QSAR models for all descriptor combinations considered for the trial molecules of Table 1 according to Equations (1) and (2), respectively.
This is confirmed by Table 2, showing the values of the same indices for the end-fire beams and for the same parameter combinations considered in Table 1.
Table 1 Yield Y 0 (mGy · mAs 1) of the reference device and α (mGy · mAs 1 · kVp 1) and β (mGy · mAs 1) for the five anode-filter combinations considered.
The procedure taken to perform the analysis and a summary of accuracy of volume counts for the factor combinations considered are presented in this paper.
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