Sentence examples for combination with targeted from inspiring English sources
Targeting tumors that overproduce Sec62 with calmodulin antagonists in combination with targeted thapsigargin analogues may offer novel personalized therapeutic options.
Moreover, selecting the appropriate chemotherapies in combination with targeted therapies or immunotherapies will be synergistic.
Clinical trials are also planned for ixabepilone in combination with targeted agents, such as trastuzumab and bevacizumab.
S1 papers take their que from previous assessments of conventional hybrids and GM (single) in combination with targeted comparative analyses of GM stacks and GM (single) plants.
We assess whether carbon pricing in combination with targeted use of the associated revenues could jointly advance Peru's long-term climate change mitigation targets and short-term socio-economic development goals.
We present clinical and radiologic data of periodontal tissue involvement preceding the appearance of osteonecrosis of the jaw (ONJ) in 5 patients with solid tumors, who received antiresorptives alone or in combination with targeted therapies.
This meta-analysis was focused on gemcitabine-based chemotherapy combinations and excluded combinations with targeted agents.
Future challenges include the optimization of dosing and toxicities when used as a single agent, and studying the safety and efficacy of combinations with targeted small molecules and other monoclonal antibodies to treat patients with melanoma and other malignancies.
However, combinations with targeted agents may allow the extended use of lower-cost hormone therapy in patients who may derive clinical benefit, allowing a delay in switching to cytotoxic chemotherapy.
Other combinations with targeted agents included bevacizumab (n = 9), sorafenib (n = 8), and pazopanib (n = 8); however, due to the small number of patients that received each of these combinations individual characterization of the outcomes of these combinations was not carried out.
Thus, although the activity of BAY 80-6946 certainly will have to be explored in additional settings, such as rationale-based combinations with targeted and chemo therapeutics, our data provide the first experimental evidence that such future studies are a worthwhile path to pursue.
