Sentence examples for combination was established from inspiring English sources
In 1871 the Grand Circuit, originally known as the Quadrilateral Trotting Combination, was established and grew from 4 to 23 tracks.
This combination was established within a phase I clinical trial with a recommended irinotecan dose of 180 mg/qm [ 15, 16].
An optimized DNA methylation combination was established through the feature selection procedure after preliminary normalization and batch effect elimination with the ComBat algorithm among the datasets to maximize the NSCLC prediction performance.
The maximum tolerated dose of the combination was established as: UFT® 350 mg m−2 day−1, LV 90 mg day−1, oxaliplatin 130 mg m−2, with grade 3 diarrhoea and grade 3 vomiting as the main dose limiting toxicities (DLTs).
Based on the productivity equation of coalbed methane (CBM) wells, three indexes, main production layer optimization index, main production layer expansion index and capacity contribution index are proposed, with which the three – step optimization method of production-layer combination is established.
One of the groups began talking to the FDA before the Office of Combination Products (OCP), which handles device-drug or device-biologic combinations, was established.
Four study combinations were established to compare the performance of different cases.
Allelic combinations were established previously by complementation testing as described in [ 19] with the following exceptions.
In order to identify the key responders to IFN-γ in this system, combinations were established where both populations can respond to IFN-γ (Fig. 6A, positive control), neither population can respond to IFN-γ (Fig. 6B, negative control), and where the IFN-γ response is restricted to either T cells or DC (Fig. 6C and D, respectively).
The superiority of combination pharmacotherapy was established in the 28-week randomized controlled Phase III EQUATE study.
Based on recent Japanese phase III trials for metastatic gastric cancer, S1 plus cisplatin combination chemotherapy was established as the standard first-line chemotherapy [ 2].
